Mac and Cheese Meatloaf Casserole

This hearty casserole combines BBQ meatloaf and creamy mac and cheese in one dish. Ground beef and sweet sauce form the base, topped with cheesy pasta and melted cheese for the perfect family dinner.

Featured in Family Dinner Ideas.

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Updated on Wed, 01 Jan 2025 17:34:58 GMT
A serving of cheesy baked macaroni and cheese with ground beef, garnished with parsley, on a white plate. Pin it
A serving of cheesy baked macaroni and cheese with ground beef, garnished with parsley, on a white plate. | quickierecipe.com

My Cozy Mac and Cheese Meatloaf Mashup

I created this recipe one chilly evening when my kids were craving both meatloaf and mac and cheese. Instead of choosing between them we combined their favorites into one amazing dish. Now it's our most requested comfort food bringing together a perfectly seasoned meatloaf base with the creamiest mac and cheese topping. This casserole brings such joy to our family dinner table.

A Recipe That Makes Everyone Happy

The magic of this casserole lies in its perfect layers. That savory meatloaf pairs so beautifully with the creamy cheesy pasta on top. It's become my go to recipe for busy weeknights since it fills everyone up and leaves them smiling. Plus the leftovers taste even better the next day.

Your Shopping List

  • Ground Beef: Get lean beef for the best flavor without excess grease.
  • Ketchup and Barbecue Sauce: Sweet Baby Rays gives the best glaze.
  • Ritz Crackers: These make our meatloaf extra special.
  • Lipton Onion Soup Mix: My secret for amazing flavor.
  • Eggs: These hold everything together perfectly.
  • Macaroni Noodles: The base for our cheesy topping.
  • Milk and Cheddar Cheese Soup: Creates the creamiest sauce.
  • Shredded Mozzarella and Cheddar: Because more cheese is better.
  • Spices: Simple seasonings that make everything pop.

Let's Get Cooking

Prepare Meatloaf:
Mix your meatloaf ingredients spread in your dish top with sauce and let it start baking.
Cook Macaroni:
Get your pasta cooking while the meatloaf starts in the oven.
Make Cheese Sauce:
Stir up that creamy cheese sauce and mix with your cooked pasta.
Assemble Casserole:
Layer that cheesy mac over your meatloaf add extra cheese and bake until bubbly.
Serve:
Give it a few minutes to settle then slice into this comfort food heaven.

My Best Kitchen Tips

Take time to spread that meatloaf mixture evenly for the best results. Always grate your own cheese it melts so much better. Watch your pasta cooking time you want it just right. A little rest time after baking makes serving much easier.

Saving Some For Later

This casserole keeps beautifully in the fridge for about 3 days or tuck it in the freezer for up to 3 months. Warm it back up in the oven for the best texture though a quick microwave works for single servings when you're in a hurry.

Making It Your Own

Feel free to use your favorite barbecue sauce or swap the Ritz for breadcrumbs. Sometimes I sneak in some veggies like sautéed onions or peppers. Try different cheese combinations my family loves it when I mix in some sharp cheddar and Monterey Jack.

Perfect Pairings

We love serving this with a crisp green salad or some steamed broccoli to balance out all that comfort food goodness. Sometimes I'll whip up some garlic bread or cornbread on the side. These little extras turn an already delicious casserole into a complete feast.

A glass baking dish filled with cheesy baked macaroni and cheese layered with ground beef. Pin it
A glass baking dish filled with cheesy baked macaroni and cheese layered with ground beef. | quickierecipe.com

Frequently Asked Questions

→ Can I make this casserole ahead of time?

You can prepare both the meatloaf and mac and cheese components separately a day ahead. When ready to serve, layer them and bake until heated through and cheese is melted. The assembled casserole might need extra time if starting from cold.

→ Can I freeze this casserole?

This casserole freezes well for up to 3 months. Thaw overnight in the fridge before reheating. Cover with foil when reheating to prevent the top from drying out, then uncover for the last few minutes to restore the crispy cheese top.

→ What can I substitute for Ritz crackers in the meatloaf?

If you don't have Ritz crackers, you can use plain breadcrumbs, crushed saltine crackers, or even quick oats. These all work well to bind the meatloaf and keep it moist. Just use about the same amount as called for in the recipe.

→ Why do you add barbecue sauce to the meatloaf?

The combination of ketchup and barbecue sauce adds both sweetness and tanginess to the meatloaf. The Sweet Baby Ray's Hickory & Brown Sugar specifically adds a rich, smoky-sweet flavor that really elevates the taste. You can adjust the ratio to suit your preference.

→ My mac and cheese seems too runny - what went wrong?

The mac and cheese will thicken as it bakes and cools slightly. Make sure to follow the exact measurements for milk and cheese soup. If it's still too runny, you can add more shredded cheese to help thicken it up, or let it sit for a few extra minutes after baking.

Mac Cheese Meatloaf

This filling casserole combines a flavorful ground beef meatloaf base topped with creamy macaroni and cheese. A perfect comfort food mashup.

Prep Time
18 Minutes
Cook Time
50 Minutes
Total Time
68 Minutes
By: Meryem

Category: Main Dishes

Difficulty: Intermediate

Cuisine: American

Yield: 8 Servings (1 casserole)

Dietary: ~

Ingredients

01 2 lbs lean ground beef.
02 30 Ritz Crackers, crushed.
03 2 oz Lipton onion soup mix.
04 2 eggs.
05 1 cup ketchup.
06 1 cup Sweet Baby Ray's Hickory & Brown Sugar barbecue sauce.
07 3 cups macaroni noodles.
08 2 cups milk.
09 10.5 oz condensed cheddar cheese soup.
10 1 tsp salt.
11 1 tsp pepper.
12 1 tbsp garlic powder.
13 1 tbsp onion powder.
14 4 cups shredded mozzarella and cheddar cheese blend.

Instructions

Step 01

Heat oven to 350°F. Mix ketchup and barbecue sauce in a bowl.

Step 02

In large bowl, combine beef, crushed Ritz crackers, onion soup mix, eggs, and 1/2 cup of sauce mixture.

Step 03

Press meatloaf mixture into greased 9x13 pan. Spread remaining sauce on top.

Step 04

Bake meatloaf for 30 minutes.

Step 05

Meanwhile, cook macaroni according to package directions.

Step 06

Mix milk and cheese soup until smooth. Add seasonings.

Step 07

Stir cooked macaroni and 2 cups cheese into milk mixture.

Step 08

Pour mac and cheese over partially cooked meatloaf.

Step 09

Top with remaining 2 cups cheese.

Step 10

Bake 17-20 minutes until cheese melts and starts browning.

Step 11

Let rest few minutes before serving.

Notes

  1. Perfect comfort food dish.
  2. Can be made ahead and reheated.
  3. Freezes well.
  4. Great for family dinners.
  5. Leftovers reheat nicely.

Tools You'll Need

  • 9x13 inch baking dish.
  • Large mixing bowls.
  • Measuring cups.
  • Pasta pot.
  • Rolling pin.

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Dairy (cheese, milk).
  • Eggs.
  • Wheat (crackers, pasta).

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 549
  • Total Fat: 22 g
  • Total Carbohydrate: 40 g
  • Protein: 45 g